Environmental factors such as lifestyle and the medications you take influence the effects your genes have on your body − and can clarify how diseases develop.
Articles on Polygenic risk score
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How to make sense of ‘polygenic’ risk scores.
Most common chronic diseases are the outcome of complex interactions between genetic, environmental and social risk factors, so a genetic risk score, on its own, isn’t much help.
Direct-to-consumer genetic testing company 23andMe is now offering a new ‘polygenic risk score’ that reveals your risk of developing Type 2 diabetes. Does it work? Are our family physicians ready?
Top contributors
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Professor of Anthropology, Deakin University
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Postdoctoral Research Associate, King's College London
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Assistant Professor of Family Medicine, University of Pittsburgh
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Lecturer in Health Ethics and Professionalism, Deakin University
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Deputy Director, Twins Research Australia & Professor in Genetics and Cell Biology, Deakin University
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Professor of Genetic Epidemiology & Statistics, King's College London
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Assistant Professor of Population and Public Health Sciences, University of Southern California