Protein structure – News, Research and Analysis – The Conversation

Rhodopsin kinase – GRK1 – is a GRK found in the retina of your eyes. Priyanka Naik

March 7, 2025

‘Pac‑Man with a ponytail’ proteins regulate everything from night vision to heartbeats – studying what GRKs look like could improve an array of drugs

Priyanka Naik, Purdue University

Master switches of cell communication, G protein-coupled receptor kinases are the target of many drugs across a range of diseases.

Imaging the proteins on the surface of HCV has been challenging because of the virus’s shape-shifting nature. Juan Gaertner/Science Photo Library via Getty Images

November 22, 2022

Scientists uncovered the structure of the key protein for a future hepatitis C vaccine – here’s how they did it

Lisa Eshun-Wilson, The Scripps Research Institute and Alba Torrents de la Peña, The Scripps Research Institute

Using a Nobel Prize-winning technique called cryo-EM, researchers were able to identify potential areas on the hepatitis C virus that a vaccine could target.

De novo protein design with deep learning can open new doors for medicine and many other fields. Kateryna Kon/Science Photo Library via Getty Images

January 5, 2022

When researchers don’t have the proteins they need, they can get AI to ‘hallucinate’ new structures

Ivan Anishchenko, University of Washington

Using a form of artificial intelligence called deep neural networks, researchers can generate new proteins from scratch without having to consult nature.

Training an algorithm to play proteins like Chopin can produce more melodious songs. Frederic Chopin/Wikimedia Commons

September 29, 2021

The music of proteins is made audible through a computer program that learns from Chopin

Peng Zhang, The Rockefeller University and Yuzong Chen, National University of Singapore

Many features of proteins are analogous to music. Mapping these features together creates new musical compositions that help researchers learn about proteins.

A simple chain of amino acids folds into a complex three-dimensional structure.

December 2, 2020

AI makes huge progress predicting how proteins fold – one of biology’s greatest challenges – promising rapid drug development

Marc Zimmer, Connecticut College

Scientists in an artificial intelligence lab have made a breakthrough in solving the problem of how proteins fold into their final three-dimensional shape. The work could speed up creation of drugs.

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