Articles on Immunology

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Two hurdles mRNA drugs face are a short half-life and impurities that trigger immune responses. Christoph Burgstedt/Science Photo Library via Getty Images

First mRNA flu shot approved by FDA bodes well for improving drugs of the future – though a few hurdles remain before mRNA can move beyond vaccines

From COVID-19 vaccines to Moderna’s mRNA flu vaccine, using mRNA as medicine has shown promise. But before mRNA drugs can go beyond vaccines, researchers need to identify the right diseases to treat.
Cyclosporiasis can cause severe gastrointestinal distress, including explosive diarrhea. wildpixel/iStock via Getty Images Plus

Cyclosporiasis sickens some people worse – why your diarrhea could be more explosive than others

Explosive diarrhea has been spreading across the US, and the parasite that causes the disease has already sickened thousands – and counting.
Scientific evidence shows that vaccines help rather than hinder our immune systems. (Mufid Majnun/Unsplash)

How vaccines give our immune systems a home advantage

The key players of our immune system aren’t well understood. Here’s how vaccines give our immune players a home advantage to fight infection.
With a little help, your immune cells can be potent tumor killers. Steve Gschmeissner/Science Photo Library via Getty Images

COVID‑19 mRNA vaccines could unlock the next revolution in cancer treatment – new research

The researchers found that mRNA-based COVID-19 vaccines could potentially help patients whose tumors don’t respond well to traditional immunotherapy.
Treg cells have been thrust into the limelight thanks to the Nobel Prize-winning work of a team of researchers from the U.S. and Japan. jarun011/iStock via Getty Images Plus

How pollution and the microbiome interact with Tregs, the immune system regulators whose discovery was honored with the Nobel Prize

Researchers are gaining insights into how external factors like air pollutants, diet and medications, and even microbes in the gut interact with regulatory T cells, for better or for worse.
Regulatory T cells (red) interact with other immune cells (blue) and modulate immune responses. National Institute of Allergy and Infectious Diseases/NIH via Flickr

How does your immune system stay balanced? A Nobel Prize‑winning answer

Regulatory T cells help your immune system distinguish between ‘self’ and ‘nonself’ – and can open doors to better treatments for cancer, autoimmune disease and transplant rejection.
Researchers are studying the potential of gold nanoparticles (yellow dots) to deliver drugs into the body. Veronika Sapozhnikova, Konstantin Sokolov, Rebecca Richards-Kortum/M.D. Anderson Cancer Center and Rice University via NIH/Flickr

Your immune system attacks drugs like it does viruses – paradoxically offering a way to improve cancer treatment

As it does with other pathogens, your immune system sees drugs as foreign invaders to be expelled from your body. But exploiting this process could reduce the side effects of chemotherapy.
The Aedes mosquito is a vector of several viral diseases, including eastern equine encephalitis, or EEE, and West Nile fever. Lee Haines

Some viruses prefer mosquitoes to humans, but people get sick anyway − a virologist and entomologist explain why

The virus that causes eastern equine encephalitis, or EEE, has evolved to infect mosquitoes. To be able to spread between people, however, it faces extra challenges.

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