Articles on Biomedical research

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NIH researchers conducted some of the earliest experiments for developing chemotherapy to treat cancer, circa 1950. National Cancer Institute, National Institutes of Health

How the NIH became the backbone of American medical research and a major driver of innovation and economic growth

The agency’s budget has grown steadily since the 1960s, fueling an industry that creates lifesaving medicines and attracts billions of dollars in investment.
The NIH is a node in an interconnected system producing health and medical advances. Anchalee Phanmaha/Moment via Getty Images

Proposed cuts to NIH funding would have ripple effects on research that could hamper the US for decades

Taxpayer-funded investment supports basic research that can yield crucial medical advancements down the line and make lifesaving drugs and technologies affordable for everyday people.
Brain organoids, pictured here, raise both many medical possibilities and ethical questions. NIAID/Flickr

Science requires ethical oversight – without federal dollars, society’s health and safety are at risk

There are several steps between research on seemingly esoteric subjects and breakthrough medical treatments. Ethical oversight at every stage ensures science and society ultimately benefit.
Divesting from the next generation of researchers means cutting the lifeblood of science and medicine. J Studios/DigitalVision via Getty Images

Cuts to science research funding cut American lives short − federal support is essential for medical breakthroughs

The National Institutes of Health has been integral to scientific progress in treating countless human diseases. Without its support, patients will ultimately pay the price.
America may not maintain its position as a global leader in biomedical research without federal support. Sean Gladwell/Moment via Getty Images

How much does scientific progress cost? Without government dollars for research infrastructure, breakthroughs become improbable

It costs money to maintain the various facilities, utilities and personnel that allow scientists to conduct research in the first place. Without federal support, institutions are left scrambling.
The lung-on-a-chip can mimic both the physical and mechanical qualities of a human lung. Wyss Institute for Biologically Inspired Engineering, Harvard University/Flickr

Organ‑on‑a‑chip models allow researchers to conduct studies closer to real‑life conditions – and possibly grease the drug development pipeline

Successes in the lab mostly don’t translate to people. Research models that better mimic the human body could close the gap.
Nanoparticles (white disks) can be used to deliver treatment to cells (blue). Brenda Melendez and Rita Serda/National Cancer Institute, National Institutes of Health

Nanomedicines for various diseases are in development – but research facilities produce vastly inconsistent results on how the body will react to them

The proteins that cover nanoparticles are essential to understanding how they work in the body. Across 17 proteomics facilities in the US, less than 2% of the identified proteins were identical.
It can be painful for researchers to read harshly worded criticism of their work from peer reviewers. (Shutterstock)

Peer review: Can this critical step in the publication of science research be kinder?

Peer review of research sounds like it should be a conversation between equals. Instead, it can be patronizing, demanding and simply unkind. A group of journal editors thinks this should change.
Preclinical research — the kind that takes place before testing on humans — often guides decisions about which potential treatments should continue to clinical trials. But attempts to replicate 50 studies found the odds of getting the same results were only about 50-50. (Pexels/Artem Podrez)

Major study shows the need to improve how scientists approach early‑stage cancer research

Preclinical studies are an important part of biomedical research, often guiding future trials in humans. Failure to replicate research results suggests a need to increase the quality of studies.

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