Up to a third of the weight lost while taking weight loss jabs such as Wegovy and Mounjaro includes muscle and bone mass.
Articles on Semaglutide
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Clinical trials show that around one in ten people are ‘non-responders’. Outside of trials, that figure might be much higher.
Wegovy might be effective at treating everything from arthritis to alcohol addiction.
A weight-loss drug more effective than Ozempic and Wegovy has recently been approved. Here’s how it works and how it compares with Ozempic.
The sellers of these online products acknowledge that many of their drugs are for ‘research purposes only’ or ‘not for human consumption.’
Patents for a drug related to Ozempic have expired, so pharmaceutical companies are working to develop ‘generic’ versions. These are likely to be much cheaper. But how do they compare with Ozempic?
The results of Novo Nordisk’s phase 1 trials shows the oral weight loss pill could be more effective than semaglutide.
The weight-loss drug Wegovy is now in Australia. Here’s what the science says about the potential benefits and risks of taking it.
Neither Ozempic nor Wegovy are listed on the PBS to treat obesity. When Wegovy becomes available, users will need to pay the full price. Or should the government subsidise it?
The animal studies are promising but early research in humans show mixed results. Here’s what we know so far.
Some women who use drugs like Ozempic have reported unexpected pregnancies. What’s going on?
Does weight come back when you stop taking drugs like Ozempic? Are these medications simply another (expensive) form of yo-yo dieting? Here’s what we know so far.
We don’t tell people taking statins to treat high cholesterol or drugs to manage high blood pressure they’re cheating or taking the easy way out. Nor should we when people take drugs like Ozempic.
In Australia, Ozempic is only approved to treat diabetes but doctors are prescribing it ‘off label’ for weight loss. Compounding pharmacies have also been making their own versions to meet demand.
Ozempic generated A$21 billion of sales in 2023 alone. So how was it developed? And how are its new competitors, Mounjaro and Zepbound, different?
Early on we heard a lot about the potential benefits of drugs like Ozempic. Now we’re hearing more about the risks. But what does the latest evidence say?
When people stopped taking one of the new weight-loss jabs they regained around 60% of their lost weight.
People who are obese, as well as those who are overweight and have weight-related issues, may soon be able to ask their doctor for a prescription.
In trials, Mounjaro was shown to be more effective than Ozempic in managing type 2 diabetes.
The Conversation has been following the trials and tribulations of semaglutide (Wegovy) as it made its way from lizard venom to blockbuster drug.
Top contributors
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Associate Professor of Metabolic Medicine, University of Surrey
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Professor of Pharmaceutical Chemistry, Macquarie University
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Professor of Community Health and Wellbeing, The University of Queensland
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Accredited Practising Dietitian and Lecturer, Southern Cross University
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Associate Professor of Physiology and Medical Education, Anglia Ruskin University
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General Practitioner, PhD Candidate, Bond University
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Head of the Translational Nanomedicine & Biotherapeutics Group and Senior Research Fellow, Adelaide University
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Distinguished Professor of Pharmacy Practice, University of Connecticut
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ARC Future Fellow, School of Biomedical Sciences, The University of Queensland
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Laureate Professor in Nutrition and Dietetics, University of Newcastle
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Assistant Professor, Critical Disability Studies, Carleton University
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Senior Lecturer, Nutrition and Food Science, Australian Catholic University
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Clinical Epidemiologist, Washington University in St. Louis
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Adjunct Senior Research Fellow, Global and Women's Health, School of Public Health & Preventive Medicine, Monash University
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Research Lead/Advanced Clinical Practitioner/Senior Research Fellow, University of Bradford