Articles on RNA therapeutics

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Two hurdles mRNA drugs face are a short half-life and impurities that trigger immune responses. Christoph Burgstedt/Science Photo Library via Getty Images

First mRNA flu shot approved by FDA bodes well for improving drugs of the future – though a few hurdles remain before mRNA can move beyond vaccines

From COVID-19 vaccines to Moderna’s mRNA flu vaccine, using mRNA as medicine has shown promise. But before mRNA drugs can go beyond vaccines, researchers need to identify the right diseases to treat.
RNA is more than just a transitional state between DNA and protein. Christoph Burgstedt/Science Photo Library via Getty Images

MicroRNA is the Nobel‑winning master regulator of the genome – researchers are learning to treat disease by harnessing how it controls genes

Victor Ambros and Gary Ruvkun won the 2024 Nobel Prize in physiology or medicine for their discovery of microRNAs, molecules that turn genes on and off – and cause disease when they go awry.

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