Treatments for uncomplicated malaria remain mostly robust. But the arsenal against severe malaria and deaths is rapidly weakening. New options are urgently required.
Articles on Chloroquine
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Ivermectin has been a lifesaving drug for people with parasitic infections like river blindness and strongyloidiasis. But taking it for COVID-19 may result in the opposite effect.
A new study not only shows that the malarial drug chloroquine doesn’t block SARS-CoV-2 from infecting lung cells, but also explains why.
When news reports tout a drug, people get interested, even if the benefits are unproven. Patient hopes, requests and demands can easily turn into real prescriptions in their doctor’s office.
During the last six months, news reports have mentioned dozens of drugs that may be effective against the new coronavirus. Here we lay out the evidence and reveal which ones are proven to work. Or not.
In the hope of finding a cure for COVID-19, it is easy to get lost in the hype. But chloroquine and hydroxychloroquine should for now be set aside.
People taking hydroxychloroquine for coronavirus may be more likely to die, according to new research. But that doesn’t mean the drug is killing them.
The US president has reignited controversy over the use of malaria drugs to guard against COVID-19. But there is little reliable evidence so far that this tactic is safe or effective.
Coronavirus drug trials are underway – a virologist explains what the treatment options may be.
To battle the coronavirus, strong regulatory protection from the FDA is essential.
The president promoted the combination of hydroxychloroquine and an antibiotic for treating COVID-19. But a new study suggests it provides no benefits.
Cinchona bark, the flavouring in tonic water, is not a natural source of chloroquine.
Taking these drugs to treat COVID-19 without medical advice has caused poisonings and death.
A medicinal chemist addresses questions about chloroquine and hydroxychloroquine: what it is, whether it is effective against COVID-19 and whether it can treat and/or prevent this disease.
Top contributors
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Professor of Chemistry and Biochemistry and President-Elect of the International Society for Antiviral Research, University of Maryland, Baltimore County
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Postdoctoral research fellow, Stellenbosch University
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Ric Day is a Friend of The Conversation.
Professor of Clinical Pharmacology, UNSW
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Professor of Medicine, University of Virginia
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Principal Research Scientist, National Institute for Medical Research (NIMR)
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Professor of Medicine, Economics and Health Promotions Science, University of Arizona
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Associate Professor of Pharmacy, University of Connecticut
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PhD Candidate, Economic Botany Collection, Royal Botanic Gardens, Kew, Royal Botanic Gardens, Kew
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Professor of Law, Boston University
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Head of School and Dean of Pharmacy, University of Sydney
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Professor of Health Policy and Internal Medicine, University of California, Davis
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Senior Lecturer in Pharmacology, Adelaide University
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Lecturer in Virology, Queen's University Belfast
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Assistant Professor of Medical Ethics, University of Pennsylvania
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University of Oxford