In a new study, a single infusion of the antidepressant – along with repeated exposure to positive imagery – significantly reduced symptoms in depressed patients in a clinical trial.
Articles on Antidepressants
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The authors of one of the most shared research papers in modern history clear up some of the misunderstandings that followed in the wake of its publication.
A recent review of studies concluded depression is not caused by a lack of serotonin in the brain. But this doesn’t mean antidepressants, which work on serotonin, aren’t effective.
Drugs can interact with one another in ways that are harmful. A study finds that taking oxycodone with certain SSRIs can make an opioid overdose more likely.
Just because we don’t understand the precise mechanism behind depression, doesn’t mean we should dismiss drugs that are known to be effective.
Different painkillers provide relief in different ways. The most effective medication is the one that best targets the type of pain you’re experiencing with minimal side effects.
Research shows that school shootings can lead to years of health, educational and economic detriment for students who survive the attack.
A well-intentioned public health message has had serious negative impacts on the treatment of young people for depression.
Drug manufacturers often shun the use of placebos in clinical trials. But research suggests that placebos could play an important role in the treatment of depression, pain and other maladies.
Some psychedelic drugs – paired with therapy – hold great potential for helping sufferers of PTSD, depression and other mental health disorders.
It’s early days yet. But here’s what we know so far.
In the study, 44% of people who stopped taking their antidepressants didn’t experience a relapse within a year.
Our new Cochrane review found antidepressants led to only small improvements in depression symptoms on average compared with placebo.
There’s buzz about MDMA – yes, the same ingredient in the street drug known as Ecstasy – being a game changer in the treatment of PTSD. A psychiatrist who treats PTSD says, “Not so fast.”
Fluvoxamine has shown positive results in early trials.
This brain region also shows how effective certain treatments will be.
In two decades, the amount of antidepressants being prescribed jumped from 4% to 11%.
Sertraline is effective at treating mild and moderate depression.
There’s a difference between having low days and feeling bad all the time. The latter is a common feature of depression.
Around 20% of young Australian women had a diagnosis of depression or anxiety in 2017 compared with 12.8% in 2009. But the proportion of people reporting significant symptoms has remained stable.
Top contributors
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Visiting Clinical Research Fellow in Psychiatry, UCL
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Professor and Personal Chair, Swansea University
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Professor of Critical and Social Psychiatry, UCL
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Assistant Director of Pharmacy, Mater Health SEQ in conjoint appointment as Associate Professor of Pharmacology, Bond University and as Associate Professor (Clinical), The University of Queensland
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Enterprise Fellow (Senior Research Fellow/Senior Lecturer), Adelaide University
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PhD candidate, School of Public Health, Monash University
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Associate Professor of Psychiatry and Psychology, University of Pittsburgh
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Head of the Department of Psychiatry, The University of Melbourne
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Professor of Biology, University of Portsmouth
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Professor of Clinical Neuropsychology, University of Cambridge
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Medical Doctor, Western Health
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Clinical Assistant Professor of Psychiatry and Neurology, University of Michigan
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Distinguished Professor of Pharmacy Practice, University of Connecticut
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Professor of Psychiatry, UNSW & Black Dog Institute, UNSW
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Professor of Psychology, The University of Melbourne