Articles on Substance use disorder

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Providing drug users with clean syringes is part of Portugal’s harm-reduction approach to substance use. Horacio Villalobos/Corbis News via Getty Images

Portugal decriminalized drugs 25 years ago, but the real lesson is what it built around this policy

Portugal’s remarkable public health strides after changing its approach to drugs may not be replicable in other countries absent broader systemic reforms.
Veterans from past wars and those returning from ongoing wars will need the country’s continued support. SDI Productions/E+ via Getty Images

Special courts helps veterans stay out of jail ‑ but staffing losses at VA and cuts to government programs are threatening their work

Many veterans struggle with addiction, mental health conditions and homelessness after military service. Veterans Treatment Courts aim to help – but they need stable funding to do so.
There is a striking lack of robust evidence that demonstrates the clinical benefits to forced treatment and confinement. Instead, research points to significant adverse effects, raising serious ethical concerns. (Adham Ragab/Unsplash)

Coercion isn’t care, and new laws that enforce treatment and confinement are dangerous

Arguing that confining and treating people against their will is ‘compassionate’ greatly expands the role of policing in medical matters, often with few limits.
There were about 3,330 overdose deaths in Pennsylvania in 2024, down from over 4,700 in 2023. Frazao Studio Latino/E+ Collection via Getty Images

New website tracks how Pennsylvania’s $2.2B in opioid settlement funds is being spent

Researchers hope that transparency around where the money is going will help counties use the funds more effectively.
Your memories are likely stored in ensembles of neurons that fire together. PASIEKA/Science Photo Library via Getty Images

Memories of the good parts of using drugs can keep people hooked − altering the neurons that store them could help treat addiction

Your brain processes the pleasure of everyday behaviors like eating and drinking similarly to the pleasure of using drugs. Disentangling them requires understanding how memories are formed.
Patients suffering withdrawal from fentanyl and xylazine can require intensive care. SDI Productions/E+ Collection via Getty Images

Philly hospitals test new strategy for ‘tranq dope’ withdrawal – and it keeps patients from walking out before their treatment is done

The combination of fentanyl and xylazine that dominates Philadelphia’s illegal dope supply creates agonizing withdrawal symptoms. This presents new challenges for doctors and nurses.
Having a beer in Raceland, La. Russell Lee for Farm Security Administration/WPA

Intoxication nation: a double shot of US history

Alcohol is a window into American history, from 17th-century rum production to young people’s declining interest in drinking today.
Considering how to reduce the impact of conflicts of interest on psychedelic studies is essential to avoid public health risks. (Shutterstock)

How corporate involvement in psychedelic research could threaten public safety

Substantial economic growth in the psychedelic drugs market has drawn interest from corporations and start-ups. While this may accelerate research, it also sparks concerns about conflicts of interest.

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