Articles on Opioid abuse

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In March 2023, the U.S. Food and Drug Administration approved naloxone as a nonprescription nasal spray to reverse the effects of an opioid overdose. Michael Siluk/UCG/Universal Images Group via Getty Images

Animal tranquilizers found in illegal opioids may suppress the lifesaving medication naloxone − and cause more overdose deaths

Increasingly, these types of tranquilizers are turning up in fentanyl, oxycodone and other illegal opioids.
Opioid neurotransmitters are located in many areas of the body, including the brain, spine and gut. ALIOUI Mohammed Elamine/iStock via Getty Images Plus

Your body naturally produces opioids without causing addiction or overdose – studying how this process works could help reduce the side effects of opioid drugs

Unlike opioid drugs like morphine and fentanyl that travel throughout the body, the opioids your body produces are released in small quantities to specific locations.
Although xylazine is not an opioid, naloxone can reverse the effects of the fentanyl and heroin it is often mixed with. AP Photo/Jae C. Hong

What is xylazine? A medical toxicologist explains how it increases overdose risk, and why Narcan can still save a life

Xylazine, or tranq, is increasingly being mixed with drugs like fentanyl or heroin and can be difficult to detect. Most people who use drugs are unable to tell if they have been exposed to it.

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