This little-known brain disorder is currently one of the biggest challenges facing medicine where age-related diseases are concerned.
Articles on Drug repurposing
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Sometimes medical breakthroughs come from unexpected places.
Ozempic-style drugs have been flagged as possible treatments for cancer, dementia, endo, addiction and more. An expert explains what the evidence really says.
Scientists are discovering that old malaria drugs and other existing medicines might help prevent cancer from returning.
AI models can help us to repurpose existing medicines, cutting research costs and timescales.
Targeting the key players that help your body regulate metabolism could reverse disease progression, including cognitive decline related to Alzheimer’s disease.
Confused by conflicting studies about the link between viagra and Alzheimer’s? Two experts explain the disparaties
Cardiovascular disease and cancer share many parallels in their origins and how they develop. Nanoparticles offer one potential way to effectively treat both with reduced side effects.
Despite technological advancements, many challenges remain in getting a drug from lab to pharmacy shelf. Reframing what is a “medicine” could expand treatment options for researchers and patients.
One of the oldest and deadliest diseases, malaria caused more than 627,000 deaths in 2020. A new treatment based on a drug initially developed to fight cancer has shown considerable promise.
Drug repurposing can redeem failed treatments and squeeze out new uses from others. But many pharmaceutical companies are hesitant to retool existing drugs without a high return on investment.
Ivermectin has been a lifesaving drug for people with parasitic infections like river blindness and strongyloidiasis. But taking it for COVID-19 may result in the opposite effect.
Top contributors
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Associate Professor of Biomedical Engineering, Michigan State University
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Senior lecturer in Pharmacoepidemiology, Aston University
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Assistant Professor of Internal Medicine and Medicinal Chemistry, University of Michigan
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Professor of Pharmaceutical Sciences, University of Colorado Anschutz
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Director of Natural Product Discovery Core; Assistant Professor of Medicinal Chemistry, University of Michigan
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Assistant Professor of History, University at Buffalo
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Assistant Professor of Biochemistry and Molecular Genetics, University of Colorado Anschutz
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Professor in Clinical Pharmacy, Aston University
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Associate Professor of Pharmacy, University of Connecticut
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Research director in parasitology, Inserm
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Docteur en pharmacie et enseignant chercheur en physiologie vasculaire, Université de Bordeaux
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Assistant Professor of Biochemistry, Penn State
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Director, Programa de Biología Computacional y Genómica Traslacional, Universidad de Navarra
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Investigador Predoctoral, Universidad de Navarra
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Senior Lecturer in Genetics and Molecular Biology, Kingston University