Vaccinating domestic dogs is a successful and cost-effective way to prevent rabies in dogs. Sarah Cleaveland September 26, 2021 Vaccinating domestic dogs reduces rabies in the wild. Why this matters Sarah Hayes, Imperial College London; Katie Hampson, University of Glasgow, and Kennedy Lushasi, Ifakara Health Institute Domestic dogs have been shown to be the only species necessary to maintain rabies across most of Africa. This means that dog vaccination should control the disease in all species.