Rohit Loomba

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A molecular model of the spike proteins (red) of SARS-CoV-2 binding to the angiotensin-converting enzyme 2 (ACE2) protein, the receptor (blue) which is its the entry route to the target cell. Juan Gaertner/Science Photo Library

What is the ACE2 receptor, how is it connected to coronavirus and why might it be key to treating COVID‑19? The experts explain

Krishna Sriram, University of California, San Diego; Paul Insel, University of California, San Diego, and Rohit Loomba, University of California, San Diego

The ACE2 receptor allows the virus that causes COVID-19 to infect and destroy our cells. What is the normal role of ACE2 in the body, and could it be the key to blocking infection?

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