Robert Centor

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Clinical guidelines can change when new research provides contradictory findings. Thomas Barwick/DigitalVision via Getty Images

Medical guidelines that embrace the humility of uncertainty could help doctors choose treatments with more research evidence behind them

Brad Spellberg, University of Southern California; Jaimo Ahn, University of Michigan, and Robert Centor, University of Alabama at Birmingham

How doctors care for their patients is highly influenced by clinical guidelines. Recommendations based on anecdotal experience or poor data can harm patients.

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