E. coli as a model organism helped researchers better understand how DNA works. Ed Horowitz Photography/The Image Bank via Getty Images

E. coli is one of the most widely studied organisms – and that may be a problem for both science and medicine

Researchers uncovered the foundations of biology by using E. coli as a model organism. But over-reliance on this microbe can lead to knowledge blind spots with implications for antibiotic resistance.
Tolerant bacteria are dormant until an antibiotic threat has passed, then reemerge to conduct business as usual. Christoph Burgstedt/Science Photo Library via Getty Images

Looming behind antibiotic resistance is another bacterial threat – antibiotic tolerance

Antibiotic resistance has contributed to millions of deaths worldwide. Research suggests that any bacteria can develop antibiotic tolerance, and possibly resistance, when pushed to their limits.

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