Katherine J Lee

2

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5

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A drug needs to pass quite a few hurdles before it gets to the market. The Conversation/Wes Mountain

Explainer: how do drugs get from the point of discovery to the pharmacy shelf?

Sabine Braat, The University of Melbourne; Elaine Mary Pascoe, The University of Queensland; Katherine J Lee, Murdoch Children's Research Institute, and Laurent Billot, UNSW

Only around 10% of new drugs in development make it onto the market. A drug needs to go through animal trials, and then four phases of human trials to be deemed suitable for use in patients.
Randomisation is the only commonly accepted method of ensuring an unbiased estimate of the treatment effect. The Conversation/Wes Mountain

Randomised control trials: what makes them the gold standard in medical research?

Katherine J Lee, Murdoch Children's Research Institute; Elaine Mary Pascoe, The University of Queensland; Laurent Billot, UNSW , and Sabine Braat, The University of Melbourne

A randomised controlled trial is the best way to compare a new treatment with the standard treatment. And randomising trial participants is a core feature of the experiment.

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