The black-legged tick is the vector that spreads Lyme disease. Its bite can infect humans with the Borrelia burgdorferi bacterium. (Jim Gathany/CDC)

Lyme disease: The pathogen’s cunning strategies for persistent infection offer clues for vaccine development

The bacterium that causes Lyme disease is a master of disguise, changing its appearance to evade the immune system as it moves from the ticks that carry it to humans or animals.

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