Harin Karunajeewa – The Conversation

Pathogens like malaria get inside our cells - so an antibiotic to combat them needs to as well. Penn State/Flickr

December 21, 2016

Weekly Dose: doxycycline treats a host of human plagues, but it won’t work forever

Harin Karunajeewa, WEHI (Walter and Eliza Hall Institute of Medical Research)

Doxycycline is an antibiotic drug that kills a wide, weird and wonderful range of bugs that are often difficult to treat with other antibiotics.

Mefloquine’s chemical structure is based on one of the first malaria drugs, quinine, that comes from the bark of South America’s Cinchona tree. Cinchona seedlings being packaged for shipment to make quinine, 1943/NLM

April 27, 2016

Weekly Dose: mefloquine, an antimalarial drug made to win wars

Harin Karunajeewa, WEHI (Walter and Eliza Hall Institute of Medical Research)

Mefloquine was one of around 250,000 chemical compounds tested for malaria-killing activity in the 1960s by the United States military who needed to protect troops from malaria in the tropics.

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