Paraxanthine is the main metabolite of caffeine. Studies suggest it can boost alertness and focus, but the research base is much smaller than for caffeine.
- Professor of Neuropharmacology, University of Lancashire
Although quitting antidepressants can cause withdrawal symptoms, they are generally less severe than those of heroin.
Pharmacies in the UK face significant cuts, so it’s perhaps not surprising that they sell many unevidenced lifestyle products.
Hallucinogens may not be as benign a previously thought, but they are a lot less harmful than alcohol.
A fentanyl vaccine is going to human clinical trials after showing promising results in rats – but here’s why it’s no cure-all for the opioid crisis.
The Alice in Wonderland mushroom is being sold online with vague promises of better health. Buyer beware.
Toxic leukoencephalopathy is when the brain’s white matter is damaged. It is often deadly.
Estima-se que as cefaleias sexuais ocorram em 1 a 1,6% da população em algum momento da vida, mas os números reais podem ser mais altos, pois muitas vezes elas não são relatadas
It’s estimated that sex headaches occur in 1-1.6% of the population at some time in their life – but the real figures could be higher as they often go unreported due to stigma around discussing sex
Having long been considered to have ‘no accepted medical use’, psychedelics are finally being recognised as being beneficial for treating a range of mental health disorders.
Psychedelic drug takers are sharing advice on Reddit on how to end a bad trip. Some of the advice is highly suspect.
Do hidromel aos cogumelos mágicos e à metanfetamina, as drogas sempre alimentaram as batalhas.
From mead to magic mushrooms to methamphetamine – drugs have always fuelled battles.
Exercising and socialising with friends may be the best kinds of activities to put on your ‘dopamine menu’.
SAD is a debilitating condition affecting many people, but there is light at the end of the tunnel.
Nitazenes were developed as a powerful class of painkiller in the 1950s, but they were abandoned – until now.
The US has seen a huge rise in drug deaths in the past decade involving a stimulant and a depressant.
Many studies have looked at the potential benefits of ayahuasca, but few have analysed its side-effects.
Fluvoxamine has shown positive results in early trials.
We’ve got better at managing the health risks of traditional drugs of abuse, but novel psychoactive substances, or ‘legal highs’, are a dangerous unknown.
Contact Colin for
- General
- Media request
- Speaking request
- Consulting / Advising
- Research collaboration
- Research supervision
- Location: Preston
- Website
- X (formerly Twitter): @colinatuclan
- Article Feed
- ORCID
- Joined
