Your physical environment, social life and lifestyle have as much an influence on your biology − and hence, how you process drugs − as your genes.
Articles on Drug optimization
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Researchers have applied AI to every step of the drug development process. But this might not be enough to design safe and effective drugs.
Despite technological advancements, many challenges remain in getting a drug from lab to pharmacy shelf. Reframing what is a “medicine” could expand treatment options for researchers and patients.
With the dual threats of antibiotic resistance and emerging pandemics, finding new drugs becomes even more urgent. A trove of medicines may be lying under our nose.
Drug development is a long and costly process that often ends in failure. Improving the way potential drug candidates are optimized could help boost success rates.
Top contributors
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Director of Natural Product Discovery Core; Assistant Professor of Medicinal Chemistry, University of Michigan
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Associate Dean for Research, Charles Walgreen Jr. Professor of Pharmacy and Pharmaceutical Sciences, University of Michigan
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Professor of Pharmaceutical Sciences, University of Colorado Anschutz
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Assistant Professor of History, University at Buffalo
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Professor of Environmental Health Sciences, Columbia University Mailman School of Public Health
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Adjunct Professor in Pharmaceutical Sciences, University of Michigan
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Assistant Professor of Biochemistry and Molecular Genetics, University of Colorado Anschutz